This course provides an in-depth introduction to white biotechnology, with a focus on enzyme engineering and directed evolution techniques. Students will explore the principles of biocatalysis, enzyme structure-function relationships, and modern approaches for optimizing enzymes for industrial applications. The course covers methodologies such as rational design, site-directed mutagenesis, and high-throughput screening, providing practical examples from current research. Special attention is given to the role of enzymes in sustainable chemical processes, including the production of biofuels, pharmaceuticals, and fine chemicals. This course is designed for MSc students in biochemistry or chemistry, offering both theoretical insights and practical experience in enzyme optimization.
Useful textbooks:
- Introduction to Enzyme Technology by K.E. Jaeger et al (Editor), 2024
- Enzyme Engineering: Selective Catalysts for Applications in Biotechnology, Organic Chemistry, and Life Science by Manfred T. Reetz, Zhoutong Sun, Ge Qu, 2023
- Kursleiter/in: Frank Schulz
Semester: WT 2024/25